Irreproducible life sciences research in U.S. costs $28 billion
Problems with preclinical studies often stem from flaws in experimental design and materials
![flaws in research](https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2015/06/lg_scistat_reproduce-01.png?fit=1030%2C551&ssl=1)
BIG SPENDERS Preclinical research is all too often irreproducible. Its flaws, which tend to stem from four broad categories, cost big bucks.
L.P. Freedman, I.M. Cockburn and T.S. Simcoe/PLOS Biology 2015, adapted by M. Telfer