Getting the picture of how someone died
CT scans of cadavers could make some autopsies unnecessary, British team suggests
By Nathan Seppa
By screening people who have died with full-body computed tomography or magnetic resonance imaging, doctors can often determine the cause of death without an autopsy, British researchers report November 22 in the Lancet. Further combining a CT scan with a quick heart test might result in a solid determination of cause of death in up to half of cases referred for autopsy, says study coauthor Ian Roberts, a pathologist at the University of Oxford.
Autopsies are invasive and sometimes inconclusive, and some people object to the procedure on cultural or religions grounds. The new data suggest that imaging may provide an alternative in some cases, adding to post-mortem accuracy and easing the burden of grieving survivors, says Roberts. Whether imaging would save money is unknown, he says.
At their essence, autopsies have changed little in the past century but remain the gold standard post-mortem exam. In recent years, some coroners and medical examiners have considered the use of medical imaging with MRI or CT scans, but few labs or hospitals have adopted the technologies because little research data existed to document their utility in this setting.
For the new study, Roberts and his colleagues examined 182 deceased people whose cause of death wasn’t known. All underwent a CT scan and MRI. Radiologists analyzed those results separately and combined, arriving at a cause of death from each set of images. The radiologists also ranked how much confidence they had in each cause-of-death conclusion — definite, probable, possible or uncertain. Pathologists then performed autopsies on all of the bodies.