In direct conflict with a controversial 2013 study, researchers say that mice may be better mimics of human inflammation than previously suggested.
The earlier study found that inflammation brought on by burns, sepsis and trauma changed gene activity very differently in mice and humans (SN: 3/23/13, p.10). But two scientists have now reanalyzed data from that study using different statistical methods. Mice and humans actually have very similar gene activity changes, the researchers report August 4 in the Proceedings of the National Academy of Sciences.