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  1. Earth

    Dead Waters

    Coastal dead zones—underwater regions where oxygen concentrations are too low for fish to survive—are mushrooming globally, threatening to transform entire ecosystems.

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  2. Math

    Playing Pig, Optimally

    The simple dice game Pig is surprisingly complex when you're trying to find an optimal strategy for playing it.

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  3. Humans

    From the May 26, 1934, issue

    Extracting bromine from the sea, a new treatment for cancer, and a novel altimeter.

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  4. Chemistry

    Chemical Knot: Scientists assemble legendary symbol by interlocking molecules

    Chemists have constructed a molecular version of a Borromean knot.

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  5. Paleontology

    Crawling through Time: Fish bones reveal past climate change

    The timing of ancient migrations of snakehead fish from the Indian subcontinent into Europe, Asia, and Africa tells scientists about temperature and humidity changes in those locations.