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  1. Health & Medicine

    Cancer Link: Gene regulates progesterone effect on breast cells

    The BRCA1 protein regulates the effect of pro-growth progesterone, which could explain why having a mutated BRCA1 gene predisposes a woman to breast cancer.

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  2. 19762

    Your article made a common mistake in characterizing the mechanism of steroid-hormone receptors. These receptors are not “proteins on the cell surface” but rather, and uniquely, positioned intracellularly. Steroid hormones pass directly from the bloodstream to the cytoplasm, where they induce changes in the receptor proteins, enable movement into the nucleus, and activate specific genes. […]

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  3. Earth

    Leaden swan song

    Large numbers of trumpeter swans are succumbing to lead poisoning as a result of ingesting old shotgun pellets in areas where use of lead shot has been banned for more than a decade.