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  1. Health & Medicine

    Taking a weight-loss drug reduced a craving for opioids

    Early results from 20 people with opioid use disorder raise hopes that popular weight-loss drugs like Wegovy can tackle opioid addiction, too.

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  2. Readers discuss quantum gravity and more

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  3. Come along with us on a mathematical mystery tour

    Editor in chief Nancy Shute discusses an unexpected breakthrough on a puzzle that has intrigued mathematicians for almost a century.

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  4. Physics

    Here’s how scientists reached nuclear fusion ‘ignition’ for the first time

    The first fusion experiment to produce an energy excess required meticulous planning and also revealed a long-predicted heating phenomenon.