50 years ago, scientists blamed migraines on cheese and chocolate

Excerpt from the August 10, 1974 issue of Science News

Close-up of woman lying down on a bed with a pained expression. Her right hand is pinching the area between her eyebrows.

Yes, an ingredient in cheese and chocolate can cause migraines. But there are also many other potential triggers, including hormone fluctuations and changes in the weather.

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Chocolate, cheese and migraines — Science News, August 10, 1974

A new study of migraine and food ingestion … is reported in the July 26 Nature. [Scientists] studied a group of migraine sufferers, administering placebos and capsules containing phenyl­ethylamine. Thirty of the 36 had no migraine reaction from the sugar capsules, while 18 of the 36 suffered a migraine attack after the phenylethylamine.

Update

Foods that contain phenylethylamine, such as chocolate and cheese, contribute to some migraines. But scientists now know that many factors, including hormone fluctuations, stress and weather changes, can trigger attacks. Certain genes have also been found to increase migraine risk (SN: 5/3/18). Although the process behind how migraines develop is still coming into focus, researchers have identified a key player in kicking things off: CGRP, a protein that helps transmit pain signals in the nervous system. Drugs targeting CGRP’s activity, first approved by the U.S. Food and Drug Administration in 2018, have provided relief for many patients (SN: 3/22/21).

Physics writer Emily Conover has a Ph.D. in physics from the University of Chicago. She is a two-time winner of the D.C. Science Writers’ Association Newsbrief award.