Genetic Culprit: Mutation increases risk for uterine fibroids
By Nathan Seppa
Analysis of DNA from families whose women have been beset by uterine growths reveals a mutation that can predispose women to these so-called fibroids.
Uterine fibroids are common, benign tumors that can cause pain, pelvic pressure, infertility, and long, heavy periods in women of childbearing age.
Their cause has been unknown. Medication that slows estrogen production can ease symptoms but doesn’t cure the problem. Many women with severe symptoms undergo hysterectomies–removal of the uterus–making fibroids the most common reason for this surgery in the United States.