Scrutinizing the first days of development in abnormal embryonic stem cells, researchers have uncovered a basic mechanism underlying fragile X syndrome, the most common inherited cause of mental retardation in boys.
“It could have important implications for treatment,” says W. Ted Brown, cochair of the scientific committee of the National Fragile X Foundation, which helped fund the work.
The research also highlights the value of embryonic stem cells for studying genetic diseases, says Yang Xu, a stem cell researcher at the University of California, San Diego.
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