Weapon of bone destruction identified
Enzyme finding may aid hunt for new anticancer therapies
![multiple myeloma in mouse bones](https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2016/08/082416_TI_bone_cancer_main.jpg?fit=860%2C460&ssl=1)
NO HOLES BARRED Mouse femurs (shown in X-rays) with multiple myeloma growing in the bone marrow develop holes and weak spots (middle, red arrows). Treating mice with a drug that inhibits an enzyme responsible for kick-starting the destruction prevents much of the bone loss (right).
H. Liu et al/Science Translational Medicine 2016