Scientists dig up proteins from the past

Evolutionary biochemists are treating ancient proteins like storytelling fossils

illustration of ancient proteins

BLAST FROM THE PAST  To learn how today’s proteins evolved, scientists are reconstructing ancient molecules.

James Provost

The influenza virus is a quick-change artist. In a few decades, its genome can evolve as much as animal genomes can over millions of years. That means that the viral proteins, including those that alert our bodies to an infection, constantly reinvent themselves, threatening our immune systems and frustrating vaccine developers.