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Achieving that understanding is the task of the architectural scholars of molecular biology, scientists who describe the loops and other yogic postures that DNA displays inside the cramped space of a cell’s nucleus. This architecture has important implications for function, perhaps by arranging the genetic furniture to enable one cell to operate as a liver cell and another to work as a skin cell. But even this 3-D appreciation of the genome is limited, as science writing intern Sarah Schwartz writes. Researchers must also contemplate a fourth dimension: genome morphing over time.